ICD Code C83.30

ICD code C83.30 is used to classify a diagnosis of diffuse large B-cell lymphoma when the specific site of the lymphoma is not specified. This code is part of the ICD-10-CM system, which is used by healthcare providers to document and report diseases and conditions for billing and statistical purposes. Diffuse large B-cell lymphoma is a type of non-Hodgkin lymphoma characterized by large cancerous B-cells that grow rapidly, and this code is applied when the location of the lymphoma within the body is not detailed in the medical record.

1. Presence of Lymphadenopathy: Swelling of lymph nodes, which may be painless, is a common symptom. It can occur in various regions such as the neck, armpits, or groin.

2. Systemic Symptoms: These include unexplained fever, night sweats, and significant weight loss, often referred to as "B symptoms" in lymphoma diagnosis.

3. Fatigue: Persistent and unexplained fatigue that does not improve with rest.

4. Abdominal Pain or Swelling: This may occur due to enlarged lymph nodes or organs such as the spleen or liver.

5. Chest Pain or Respiratory Issues: Difficulty breathing or chest pain may occur if lymph nodes in the chest are affected.

6. Blood Test Abnormalities: Abnormal blood counts, such as anemia or elevated lactate dehydrogenase (LDH) levels, which may indicate increased cell turnover.

7. Biopsy Confirmation: A definitive diagnosis is often made through a biopsy of the affected lymph node or tissue, revealing the presence of large B-cells.

8. Imaging Studies: CT, PET, or MRI scans showing masses or enlarged lymph nodes in various parts of the body.

9. Bone Marrow Involvement: In some cases, a bone marrow biopsy may be necessary to determine the extent of disease involvement.

10. Absence of Specific Site Identification: The diagnosis is made without specifying the exact site of the lymphoma, indicating it is unspecified.

For the ICD code C83.30, which pertains to diffuse large B-cell lymphoma, unspecified site, the relevant CPT codes that may be applicable for treatment and management include:

1. 96413 - Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug.

2. 96415 - Chemotherapy administration, intravenous infusion technique; each additional hour (list separately in addition to code for primary procedure).

3. 96417 - Chemotherapy administration, intravenous infusion technique; each additional sequential infusion (different substance/drug), up to 1 hour.

4. 96365 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour.

5. 96366 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (list separately in addition to code for primary procedure).

6. 96367 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); additional sequential infusion of a new drug/substance, up to 1 hour.

7. 96368 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); concurrent infusion.

8. 96401 - Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic.

9. 96402 - Chemotherapy administration, subcutaneous or intramuscular; hormonal anti-neoplastic.

These CPT codes are commonly used in the treatment of conditions like diffuse large B-cell lymphoma and may vary based on the specific treatment regimen and clinical scenario. Always ensure to verify with the latest coding guidelines and payer-specific requirements.

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