ICD Code D49.6
ICD code D49.6 is used to identify a neoplasm of unspecified behavior in the brain, meaning the tumor’s nature is not clearly defined.
Boost patient experience and your bottom line by automating patient cost estimates, payer underpayment detection, and contract optimization in one place.
What is ICD diagnosis code D49.6
ICD code D49.6 is a diagnosis for a brain tumor whose behavior—whether benign, malignant, or uncertain—has not been specified.
When to use ICD code D49.6
1. Presence of a brain lesion identified through imaging studies (CT, MRI) that is confirmed to be a neoplasm
2. Histopathological evaluation is inconclusive or not performed, leaving the behavior (benign, in situ, malignant) of the neoplasm undetermined
3. Clinical presentation may include neurological symptoms such as headaches, seizures, cognitive changes, or focal neurological deficits
4. No definitive evidence of metastatic disease or primary malignancy elsewhere
5. The neoplasm does not meet criteria for classification as benign, in situ, or malignant based on current clinical and diagnostic findings
Billable CPT codes for ICD code D49.6
Applicable CPT codes for ICD code D49.6 may include:
- 61510: Craniectomy or craniotomy, for excision of brain tumor, supratentorial, except meningioma
- 61512: Craniectomy or craniotomy, for excision of brain tumor, infratentorial or posterior fossa
- 61796: Stereotactic computer-assisted (navigational) procedure; cranial lesion
- 61798: Stereotactic computer-assisted (navigational) procedure; cranial, with excision or ablation
- 70551: MRI, brain, without contrast
- 70553: MRI, brain, without and with contrast
- 77011: Magnetic resonance guidance for stereotactic localization
- 99204–99205: New patient office or other outpatient visit (for initial evaluation)
- 99214–99215: Established patient office or other outpatient visit (for follow-up care)
Are you being underpaid for encounters with D49.6
Schedule a demo to see how MD Clarity’s RevFind software can read your contracts and automatically detect underpayments for CPT codes related to ICD code D49.6. Ensure your organization is paid accurately—discover how RevFind can help you identify missed revenue opportunities today.
Get paid in full by bringing clarity to your revenue cycle
Related ICD Codes
Subscribe to the

Healthcare Clarified newsletter
Get the latest insights on RCM and healthcare policy in your inbox