ICD Code C83.39

ICD code C83.39 is diffuse large B-cell lymphoma that occurs in extranodal and solid organ sites, meaning the cancer originates outside of the lymph nodes, such as in organs or other tissues.

1. Presence of a malignant lymphoid neoplasm composed of large B-cells

2. Histopathological confirmation of diffuse large B-cell lymphoma

3. Lymphoma involvement identified in extranodal sites or solid organs (e.g., gastrointestinal tract, skin, bone, central nervous system, testis, or other non-lymphatic tissues)

4. Absence of primary nodal involvement as the main disease site

5. Clinical symptoms may include rapidly enlarging mass, B symptoms (fever, night sweats, unexplained weight loss), or organ-specific symptoms depending on the extranodal site involved

6. Imaging and/or biopsy confirming disease localization to extranodal or solid organ sites

Relevant CPT codes that may be used to treat ICD code C83.39 include:

- 96413: Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug

- 96415: Chemotherapy administration, intravenous infusion technique; each additional hour

- 96417: Chemotherapy administration, intravenous infusion technique; each additional sequential infusion (different substance/drug), up to 1 hour

- 96409: Chemotherapy administration, intravenous, push technique, single or initial substance/drug

- 96411: Chemotherapy administration, intravenous, push technique, each additional substance/drug

- 96401: Chemotherapy administration, subcutaneous or intramuscular, non-hormonal anti-neoplastic

- 96405: Chemotherapy administration, intralesional, up to and including 7 lesions

- 96406: Chemotherapy administration, intralesional, more than 7 lesions

- 36591: Collection of blood specimen from a completely implantable venous access device

- 36592: Collection of blood specimen using established central or peripheral catheter, venous, not otherwise specified

- 38500: Biopsy or excision of lymph node(s); open, superficial

- 38525: Biopsy or excision of lymph node(s); open, deep axillary node(s)

- 88305: Level IV - Surgical pathology, gross and microscopic examination

CPT code selection should be based on the specific treatment modality and clinical scenario.

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