ICD Code C91.10

ICD code C91.10 is used to identify chronic lymphocytic leukemia (CLL) of B-cell type in patients who have not achieved remission. This code is part of the International Classification of Diseases (ICD) system, which is used by healthcare providers to classify and code all diagnoses, symptoms, and procedures. Specifically, C91.10 indicates that the patient has a type of leukemia that affects the B-cells, a type of white blood cell, and that the disease is currently active, as the patient has not yet reached a state of remission. This code is crucial for accurate medical documentation, billing, and treatment planning.

1. Persistent Lymphocytosis: The patient exhibits a sustained increase in lymphocyte count, typically greater than 5,000 lymphocytes per microliter of blood, over a period of several months.

2. Bone Marrow Involvement: Bone marrow biopsy reveals infiltration by small, mature-appearing lymphocytes, often exceeding 30% of nucleated cells.

3. Immunophenotyping: Flow cytometry analysis shows a characteristic immunophenotype with expression of CD5, CD19, CD20 (dim), and CD23 on B-cells, along with weak expression of surface immunoglobulin.

4. Absence of Remission: The patient has not achieved remission, indicating that the disease is still active and has not responded to treatment or has not been treated yet.

5. Clinical Symptoms: The patient may present with symptoms such as fatigue, night sweats, weight loss, or lymphadenopathy, although some patients may be asymptomatic at diagnosis.

6. Cytogenetic Abnormalities: Genetic testing may reveal common chromosomal abnormalities associated with the condition, such as deletions in chromosomes 13q, 11q, or 17p, or trisomy 12.

7. Hematological Findings: Blood tests may show anemia or thrombocytopenia, which are indicative of bone marrow involvement and disease progression.

8. Organomegaly: Physical examination or imaging studies may reveal splenomegaly or hepatomegaly, indicating organ involvement.

9. Recurrent Infections: The patient may experience frequent infections due to compromised immune function, a common complication of the condition.

10. Family History: A family history of similar hematological disorders may be present, suggesting a genetic predisposition.

For the ICD code C91.10, which pertains to chronic lymphocytic leukemia of B-cell type not having achieved remission, the relevant CPT codes that may be applicable for treatment and management include:

1. CPT 96401 - Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic.

2. CPT 96402 - Chemotherapy administration, subcutaneous or intramuscular; hormonal anti-neoplastic.

3. CPT 96413 - Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug.

4. CPT 96415 - Chemotherapy administration, intravenous infusion technique; each additional hour (list separately in addition to code for primary procedure).

5. CPT 96416 - Chemotherapy administration, intravenous infusion technique; initiation of prolonged chemotherapy infusion (more than 8 hours), requiring use of a portable or implantable pump.

6. CPT 96417 - Chemotherapy administration, intravenous infusion technique; each additional sequential infusion (different substance/drug), up to 1 hour (list separately in addition to code for primary procedure).

7. CPT 96365 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour.

8. CPT 96366 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (list separately in addition to code for primary procedure).

9. CPT 96367 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); additional sequential infusion of a new drug/substance, up to 1 hour (list separately in addition to code for primary procedure).

10. CPT 96368 - Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); concurrent infusion.

These CPT codes are commonly used in the treatment and management of conditions associated with ICD code C91.10, and healthcare providers should ensure accurate coding to facilitate proper billing and reimbursement processes.

Discover how MD Clarity's RevFind software can enhance your revenue cycle management by accurately reading your contracts and detecting underpayments for CPT codes associated with ICD code C91.10. Schedule a demo today to see how RevFind can ensure you're receiving the full reimbursement you deserve.