ICD Code C92.10

ICD code C92.10 is chronic myeloid leukemia that tests positive for the BCR/ABL gene abnormality and has not yet responded to treatment or achieved remission.

1. Presence of BCR/ABL gene fusion (Philadelphia chromosome positive) confirmed by cytogenetic or molecular testing

2. Diagnosis of chronic myeloid leukemia (CML) established by hematopathology

3. Patient has not achieved hematologic, cytogenetic, or molecular remission

4. Persistent leukocytosis, often with increased granulocytes and basophils

5. Symptoms may include fatigue, weight loss, night sweats, or splenomegaly

6. No evidence of accelerated phase or blast crisis

Relevant CPT codes for ICD code C92.10 include:

- 81206 (BCR/ABL1, major breakpoint, qualitative or quantitative)

- 81207 (BCR/ABL1, minor breakpoint, qualitative or quantitative)

- 81208 (BCR/ABL1, other breakpoints, qualitative or quantitative)

- 36415 (Collection of venous blood by venipuncture)

- 85025 (Complete blood count, automated, and automated differential WBC count)

- 88184 (Flow cytometry, first marker)

- 88185 (Flow cytometry, each additional marker)

- 88377 (Morphometric analysis, in situ hybridization, each probe)

- 96413 (Chemotherapy administration, intravenous infusion, up to 1 hour, single or initial substance/drug)

- 96415 (Chemotherapy administration, intravenous infusion, each additional hour)

- 96372 (Therapeutic, prophylactic, or diagnostic injection, subcutaneous or intramuscular)

These codes are commonly used in the management and treatment of patients with ICD code C92.10.

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