ICD Code D57.1
ICD code D57.1 is used to identify sickle-cell disease without crisis for accurate diagnosis and medical recordkeeping.
Boost patient experience and your bottom line by automating patient cost estimates, payer underpayment detection, and contract optimization in one place.
What is ICD diagnosis code D57.1
ICD code D57.1 is sickle-cell disease without crisis, meaning the patient has sickle-cell disease but is not currently experiencing an acute episode or complication such as pain crisis or organ damage.
When to use ICD code D57.1
1. Patient has a confirmed diagnosis of sickle-cell disease (hemoglobin S).
2. No evidence of acute pain crisis or vaso-occlusive crisis at the time of encounter.
3. No current complications such as acute chest syndrome, splenic sequestration, or stroke.
4. Patient may present for routine follow-up, management, or monitoring of sickle-cell disease.
5. Absence of symptoms indicating acute exacerbation, such as severe pain, fever, or acute organ dysfunction.
Billable CPT codes for ICD code D57.1
Relevant CPT codes that may be used to treat ICD code D57.1 include:
- 99201–99499 (Evaluation and Management services)
- 36415 (Collection of venous blood by venipuncture)
- 96372 (Therapeutic, prophylactic, or diagnostic injection)
- 96365–96368 (Intravenous infusion, for therapy, prophylaxis, or diagnosis)
- 85025 (Complete blood count with automated differential)
- 80050 (General health panel)
- 80053 (Comprehensive metabolic panel)
- 83020 (Hemoglobin electrophoresis)
- 96360–96361 (Intravenous infusion, hydration)
- 96374 (Therapeutic, prophylactic, or diagnostic injection, intravenous push)
CPT code selection should be based on the specific services rendered for ICD code D57.1.
Are you being underpaid for encounters with D57.1
See how MD Clarity’s RevFind software can automatically read your contracts and identify underpayments for CPT codes associated with ICD code D57.1. Schedule a demo today to ensure you’re capturing the full reimbursement you deserve.
Get paid in full by bringing clarity to your revenue cycle
Related ICD Codes
Subscribe to the

Healthcare Clarified newsletter
Get the latest insights on RCM and healthcare policy in your inbox
