ICD Code E21.0

ICD code E21.0 is primary hyperparathyroidism, a condition where the parathyroid glands produce too much parathyroid hormone, leading to elevated calcium levels in the blood.

1. Elevated serum calcium levels (hypercalcemia) detected on laboratory testing

2. Increased parathyroid hormone (PTH) levels in the presence of hypercalcemia

3. Absence of other causes of hypercalcemia, such as malignancy or medication-induced

4. Evidence of parathyroid gland abnormality (e.g., adenoma, hyperplasia) on imaging or surgical exploration

5. Symptoms or complications related to hypercalcemia, such as nephrolithiasis, bone pain, osteoporosis, gastrointestinal disturbances, or neuropsychiatric symptoms

6. Chronicity of findings, with persistent hypercalcemia and elevated PTH over time

Relevant CPT codes that may be used to treat ICD code E21.0 include:

- 60500: Parathyroidectomy or exploration of parathyroid(s)

- 60502: Parathyroidectomy or exploration of parathyroid(s), re-exploration

- 60505: Parathyroid autotransplantation

- 82938: Parathyroid hormone (PTH), immunoassay

- 76942: Ultrasonic guidance for needle placement (for localization procedures)

- 78070: Parathyroid imaging, planar, with or without SPECT

These CPT codes are commonly associated with the management and treatment of E21.0.

See how MD Clarity’s RevFind software can automatically read your payer contracts and identify underpayments for CPT codes associated with ICD code E21.0. Schedule a demo today to ensure you’re capturing every dollar your practice has earned.