ICD Code E21.5

ICD code E21.5 is a diagnosis for an unspecified disorder of the parathyroid gland, meaning the patient has a parathyroid condition that is not further defined or specified in the medical record.

1. Presence of abnormal calcium or phosphate metabolism without a clearly defined parathyroid disorder

2. Laboratory evidence of altered parathyroid hormone (PTH) levels without a specific diagnosis (e.g., not clearly hyperparathyroidism or hypoparathyroidism)

3. Clinical symptoms suggestive of parathyroid dysfunction, such as unexplained muscle weakness, fatigue, bone pain, or neuropsychiatric disturbances

4. Imaging or diagnostic studies indicating parathyroid gland abnormality without a definitive classification

5. Exclusion of other specific parathyroid disorders (e.g., adenoma, carcinoma, hyperplasia)

6. Persistent or recurrent symptoms related to calcium imbalance with inconclusive etiology after standard workup

Relevant CPT codes that may be used to treat ICD code E21.5 include:

- 82310 (Calcium; total)

- 82330 (Calcium; ionized)

- 83970 (Parathyroid hormone [PTH])

- 84100 (Phosphorus inorganic [phosphate])

- 84436 (Thyroxine; total)

- 84439 (Thyroid stimulating hormone [TSH])

- 60500 (Parathyroidectomy or exploration of parathyroid(s))

- 60505 (Parathyroidectomy, re-exploration)

- 60512 (Parathyroid autotransplantation)

These CPT codes are commonly associated with the evaluation and management of E21.5.

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