ICD Code E88.09

ICD code E88.09 is used to identify other disorders of plasma-protein metabolism that are not classified elsewhere, covering a range of rare or unspecified abnormalities in the way the body processes plasma proteins.

1. Presence of abnormal plasma protein levels not attributable to more specific, classified disorders

2. Laboratory evidence of dysproteinemia without a definitive diagnosis such as amyloidosis, paraproteinemia, or specific immunoglobulinopathies

3. Clinical findings suggestive of plasma protein metabolism disorder, such as unexplained edema, hyperviscosity, or abnormal coagulation, with exclusion of other defined conditions

4. Symptoms or laboratory abnormalities indicating protein imbalance, such as hypoalbuminemia or hypergammaglobulinemia, not explained by liver, renal, or infectious etiologies

5. Absence of diagnostic criteria for more specific plasma protein disorders (e.g., multiple myeloma, Waldenström macroglobulinemia, or hereditary angioedema)

6. Documentation of a plasma protein abnormality that does not fit criteria for any other ICD-coded disorder

Relevant CPT codes that may be used to treat ICD code E88.09 include:

80050, 80053, 80061, 82040, 82150, 82247, 82248, 82306, 82746, 83036, 84155, 84165, 84443, 84450, 84460, 84520, 85025, 86003, 86334, 86335, 86336, 86337, 86352, 86353, 86376, 86378, 86386, 86390, 86485, 86580, 86696, 86703, 86800, 86803, 86850, 86860, 86900, 86901, 86910, 86920, 86921, 86927, 86930, 86931, 86932, 86945, 86950, 86960, 87040, 87070, 87075, 87081, 87102, 87116, 87147, 87149, 87205, 87207, 87210, 87220, 87252, 87253, 87254, 87255, 87270, 87272, 87273, 87274, 87275, 87276, 87277, 87278, 87279, 87280, 87281, 87285, 87290, 87299, 87320, 87324, 87327, 87328, 87329, 87330, 87331, 87332, 87333, 87334, 87335, 87336, 87337, 87338, 87339, 87340, 87341, 87342, 87343, 87344, 87345, 87346, 87347, 87348, 87349, 87350, 87351, 87352, 87353, 87354, 87355, 87356, 87357, 87358, 87359, 87360, 87361, 87362, 87363, 87364, 87365, 87366, 87367, 87368, 87369, 87370, 87371, 87372, 87373, 87374, 87375, 87376, 87377, 87378, 87379, 87380, 87381, 87382, 87383, 87384, 87385, 87386, 87387, 87388, 87389, 87390, 87391, 87392, 87393, 87394, 87395, 87396, 87397, 87398, 87399

These codes are subject to clinical judgment and payer guidelines.

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