ICD Code K21.0

ICD code K21.0 is gastro-esophageal reflux disease (GERD) with esophagitis, meaning stomach acid is flowing back into the esophagus and causing inflammation or irritation of the esophageal lining.

1. Presence of recurrent heartburn or acid regurgitation

2. Evidence of esophageal mucosal injury or inflammation confirmed by endoscopy

3. Symptoms such as chest pain, dysphagia, or odynophagia associated with reflux

4. Histological findings of esophagitis on biopsy, if performed

5. Exclusion of other causes of esophagitis (e.g., infection, medication-induced, eosinophilic esophagitis)

6. Chronic or persistent symptoms despite lifestyle modification or initial therapy

Relevant CPT codes for ICD code K21.0 include:

- 43235: Esophagogastroduodenoscopy (EGD) diagnostic, with or without collection of specimen(s) by brushing or washing

- 43239: EGD with biopsy, single or multiple

- 43248: EGD with insertion of guide wire followed by dilation of esophagus

- 91010: Esophageal motility study

- 91035: Esophagogastric junction study, e.g., impedance planimetry

- 91034: Esophageal function test, gastroesophageal reflux test with recording, interpretation, and report

- 91038: Esophageal pH monitoring, with interpretation and report

- 43250: EGD with removal of tumor(s), polyp(s), or other lesion(s) by hot biopsy forceps

These CPT codes may be used in the treatment or management of ICD code K21.0.

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