ICD Code R53

ICD code R53 is used to indicate weakness or malaise, which refers to general feelings of tiredness, lack of energy, or fatigue that are not specific to a particular disease.

1. Presence of generalized weakness or fatigue not attributable to a specific disease process

2. Patient reports persistent tiredness or lack of energy

3. Symptoms are not explained by acute illness, infection, or identifiable medical condition

4. Clinical evaluation rules out other specific causes of malaise or fatigue

5. Documentation of subjective complaints such as feeling run down, exhausted, or lacking motivation

6. Symptoms may be chronic or subacute in onset and are not associated with exertion alone

7. No evidence of psychiatric or neurological disorder as the primary cause

Relevant CPT codes that may be used to treat ICD code R53 include:

- 99201–99215 (Evaluation and Management services)

- 93000 (Electrocardiogram, routine ECG with at least 12 leads; with interpretation and report)

- 36415 (Collection of venous blood by venipuncture)

- 80050 (General health panel)

- 81000–81003 (Urinalysis)

- 85025 (Complete blood count with automated differential WBC count)

- 84443 (Thyroid stimulating hormone [TSH])

- 96372 (Therapeutic, prophylactic, or diagnostic injection; subcutaneous or intramuscular)

The selection of CPT codes should be based on the provider’s clinical judgment and the patient’s specific presentation.

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